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Norco is a prescription pain medication that combines hydrocodone and acetaminophen. It is used to manage moderate to severe pain. Hydrocodone, the opioid component, alters the brain’s response to pain, while acetaminophen enhances pain relief and reduces fever. Norco can be highly effective, but it carries a risk of dependence, especially with long-term use. Common side effects include drowsiness, nausea, and constipation. Due to the potential for addiction and liver damage from acetaminophen, it should be used only as prescribed and for the shortest duration necessary.